Lab of Data pharmacognosy
Natural Products & AI Research for Drug Discovery from Nature
News
2024.12.04.
Our first Vision transformer-based approach is now published!!
My group has attempted to apply computer vision techniques to mass spectrometry and achieved modest but promising results, demonstrating that computer vision can assist in annotating structural isomer cases in mass spectrometry.
We are going to expand this approach to solve various challenges in mass spectrometry!
2024.12.02.
Grand re-opening!!
Our laboratory has been moved into the new (and larger) place!!
The new HVAC system designed by professional engineers provides clean air and a safe laboratory environment! Additionally, by separating research spaces from laboratory areas, it is expected to protect the health of members and enhance research efficiency.
2024.09.01.
Welcome Jingxu (경훤) & Oju!!!
Our new members, Jingxu (경훤) and Oju joined our lab :)
Now, they are working on the discovery of bioactive natural products from Korean endemic plants! Good Luck!!
2024.07.03.
Jiin was awarded the Excellent Poster Presentation Award from the 2024 Spring International Convention of PSK!!
Jiin's poster, "Advanced Mass Spectrometry Analysis of Positional Isomers in Flavonoid Glycosides using Deep Neural Networks" was awarded as the excellent posters in the 2024 Spring International Convention of PSK!!
Congrats ! Jiin !!
2024.02.13.
Welcome Young hoon!!!
Our new member, Young hoon joined our lab :) He was a student scientist last year, and worked on the quality control of herbal medicine based on the KFDA guideline! We have high expectation of his contribution to our lab!!
2024.01.29.
UHPLC-QqQ-MS/MS system is now available!
A triple quadrupole (TQ or QqQ) MS system is used to quantify components of a bio-sample or to analyze their structure with increased specificity and sensitivity, by using two mass filtration steps in series, separated by a collision cell. It enables precise quantification of even small amounts of molecules!
2023.12.04.
NPClassifier paper has been listed on the highly cited papers at BRIC!!
NPClassifier is a deep-learning tool for the automated structural classificaiton of natural products based on their counted Morgan figerprints. The paper has now been cited over 120 times across various research fields!
2023.11.10.
Kyu Hyeong was awarded the Excellent Poster Presentation Award from the 2023 Fall International Convention of PSK!!
Kyu Hyeong's poster, "Exploration of biologically active compounds from native Korean plants for cosmeceutical development using UPLC-QTOF-MS and Molecular Networking : Iridoids from Veronica longifolia" was chosen as one of the excellent posters in the 2023 Fall International Convention of PSK!!
Congrats! Kyu Hyeong!!
2023.11.08.
Our lab was awarded the innovative research lab initiation grant from NRF!
New protein purification system (Fast Protein Liquid Chromatography, FPLC) has been installed in our lab! This valuable system will accelerate our targeted approach to discover protein-binding ligand from natural products!
2023.10.22.~10.24
Our lab has joined the 2023 Fall International Convention of PSK in Suncheon!!
Beautiful scenery of Suncheonman and the latest pharmacetical technolgy were really impressive to all of us :)
2023.10.16.
Refractive Index (RI) Detector system is now available!!
Refractive index (RI) detection is the standard approach for quantitatively detecting sugars via high-performance liquid chromatography (HPLC).
It can be applied to detect and isolate UV-undetectable bioactive natural products with no UV absorbance as well!
So powerful!!
2023.10.06.
New Biotage® MPLC System has been installed!
Higher pressure (140 psi) conditions can be applied to the pre-preparative process for the complex natural product crude extract!!
It will make our study more efficient by saving time!
2023.08.21.
Welcome Seung Hyun!!!
Our new member, Seung Hyun joined our lab :) She has worked on soil bacteria research during undergraduate. Her experience would be a great help to discover various natural products from soil. Welcome!
2023.04.20.~04.21.
Our lab joined the 2023 Spring International Convention
of The Pharmaceutical Society of Korea in Gyeong-ju!!
It was a super-cool conference to communicate with extraordinary researchers from various pharmaceutical reserach fields!!
2023.03.01.
Our lab was awarded the outstanding young scientist grant!!
National Research Foundation of Korea will support our research titled
"Target-based natural product discovery from Korean indigenous natural products using A.I. and metabolomics" for next five years! Congrats!!
2023.02.20.
Here comes a new member!! Welcome Ji In!
Our new member, Ji In joined our lab :) She has worked on quality control of drugs using ICP-MS system before. Welcome!
2022.12.01.
Two intruments have been set up!!
HPLC and MPLC have been set up in our laboratory!
These intruments will guide us from the complexity of natural products!
2022.11.03. - 04.
Our group attended the 53rd KSP annual meeting!
Myung Ji and Kyu Hyeong gave poster presentation about
"A new cyclohexenone ester from Idesia polycarpa".
Great job!
2022.10.01.
Several cyanobacteria species have been provided!
Those tropical cyanobacteria are being cultured in our lab!
Hopefully, they are growing well and producing lots of bioactive metabolites!
2022.09.16.
Visiting the medicinal plant garden with undergraduates!
Our lab members and the undergraduates of Dongguk University visited the medicinal herb garden of Seoul National University for the field practice!
Hundreds of medicinal plants welcomed us :)
2022.08.22.
Kyu Hyeong & Myeong Ji joined our lab together!
Two fascinating researchers, Kyu Hyeong and Myeong Ji came and joined the Kim laboratory from this August. Welcome!!
2022.07.30.
Prof. Dr. Kim attended the ASP 2022 meeting as a contributed speaker.
Hyunwoo joined the meeting and introduced the DeepSAT, a convolutional neural network-based structure annotation tool.
2022.07.01.
High Performance Liquid Chromatography (HPLC) system is now available!!
HPLC system equipped with auto-injector and fraction collector has been set up in our laboratory! This system allows us to isolate and purify the natural products!
2022.06.01.
Congratulations! Our lab was awarded "Basic Science Research Program" grant funding!!
National Research Foundation of Korea will support our research titled "Facilitating The Discovery of Bioactive Natural Products Using Convolutional Neural Network and Molecular Networking Analysis".
2022.04.01.
Congratulations! Our lab has joined the IMRCTR project!
The IMRCTR (Innovative Medicine Research Center for Tumor Remission) has worked on the discovery of novel regulator for cancer therapy!
Our lab will contribute this project by finding novel natural products and developing virtual screening tools for anti-cancer drug discovery.
2022.03.01.
Hello world!!!
Our lab opened at College of Pharmacy, Dongguk University, Goyang, Korea